The structure of cancer research can be complex,even as the disease itself is.As a case in point,consider that MedImmune,the biotech division of British pharmaceutical titan AstraZeneca,has agreed to contribute three of its monoclonal antibodies to a research effort of the Cancer Vaccine Collaborative,or CVC.The CVC is in turn a project sponsored by a philanthropic organisation called the Cancer Research Institute and also by the Ludwig Institute for Cancer Research.The CVC is a network of clinical immunologists and oncologists with expertise in immunotherapy programs.
MedImmune's three antibodies will be incorporated into the CVC's portfolio of cutting edge clinical research and development,which utilises the expertise of its global network of clinicians and scientists to identify new immunotherapy combinations and launch clinical trials that help to bring the new treatments to cancer patients faster.
MedImmune's antibodies will be combined with other primary agents available to the CVC or accessed through additional partnerships to develop a more powerful generation of smarter immunotherapy drugs to better manage cancer patients' disease over the long term.Such combinations enable scientists to attack a particular cancer on multiple fronts,increasing the effectiveness of immune system response to cancer.
A monoclonal antibody is a protein produced from a single cell clone that can bind to substances such as tumor cells or other proteins,thus stimulating a person's immune system,modifying its regulatory checkpoints to make it more effective in responding to cancer.MedImmune intends to continue its research on these antibodies on an individual basis while the CVC combination studies proceed.
No financial terms of the joint effort with the CVC were revealed.
MedImmune employs about 3500 people worldwide.Its headquarters are in Gaithersburg,Maryland.
AstraZeneca(AZN)
Friday, October 12, 2012
Tuesday, October 9, 2012
Should You Buy Citigroup Shares
Citigroup has a competitive advantage,in the view of David Konrad,CFA,Managing Director at Keefe,Bruyette and Woods.They will be able to sell Citi Holdings,their troubled assets,and are doing well at this time of growing trade finance.Citi is improving its Basel III captial ratio.
The drag of Citi Holdings will decline each year,easing significantly over the next few years.The bad bank will take five years to entirely dissolve.In about two years,Citi Holdings will be less than 10% of Citigroup.
The stock will rally 33%.We do a lot of stress models,and we think the capital is there.The transparency has gotten better over the past year.KBW has upgraded Citigroup to outperform,with a price target of 44 dollars.
Keefe,Bruyette and Woods is a full service boutique investment bank.Its specialty is the financial services sector.
Citigroup closed at 34.78 on Monday.
Citigroup(C),Keefe Bruyette and Woods(KBW)
The drag of Citi Holdings will decline each year,easing significantly over the next few years.The bad bank will take five years to entirely dissolve.In about two years,Citi Holdings will be less than 10% of Citigroup.
The stock will rally 33%.We do a lot of stress models,and we think the capital is there.The transparency has gotten better over the past year.KBW has upgraded Citigroup to outperform,with a price target of 44 dollars.
Keefe,Bruyette and Woods is a full service boutique investment bank.Its specialty is the financial services sector.
Citigroup closed at 34.78 on Monday.
Citigroup(C),Keefe Bruyette and Woods(KBW)
Monday, October 8, 2012
Asia This Day:More Trouble At Foxconn;Chinese Stocks Cheap
The Southern European shock has had a very sizable global impact,according to Stephen King,HSBC Group Chief Economist.We're not seeing the same kind of China boost this time around.HSBC predicts 8.6% China growth,with global growth at 2.2% for 2012.
The number of Australian help wanted ads were down for the sixth straight month,says ANZ Bank.
Japanese markets are closed today for Fitness Day,while Chinese markets reopened after a week-long holiday.Chinese stocks are the cheapest they've been since 1997.Hong Kong's Hang Seng index was down 0.70 in Monday morning trading.
At a Foxconn factory in Zhengzhou,China,workers returned to their jobs today after 3-4,000 walked off Friday,closing down two shifts.They had gotten upset when quality control said they were scratching too many Apple iPhone 5 casings.This follows a riot the week before at another Foxconn plant in Taiyuan that also makes iPhone 5 casings.
The Zhengzhou workers complained that new quality standards for iPhone casings were beyond the limit of their vision.A ruckus broke out over the issue resulting in property damage,injury and hospitalisation.
The number of Australian help wanted ads were down for the sixth straight month,says ANZ Bank.
Japanese markets are closed today for Fitness Day,while Chinese markets reopened after a week-long holiday.Chinese stocks are the cheapest they've been since 1997.Hong Kong's Hang Seng index was down 0.70 in Monday morning trading.
At a Foxconn factory in Zhengzhou,China,workers returned to their jobs today after 3-4,000 walked off Friday,closing down two shifts.They had gotten upset when quality control said they were scratching too many Apple iPhone 5 casings.This follows a riot the week before at another Foxconn plant in Taiyuan that also makes iPhone 5 casings.
The Zhengzhou workers complained that new quality standards for iPhone casings were beyond the limit of their vision.A ruckus broke out over the issue resulting in property damage,injury and hospitalisation.
Friday, October 5, 2012
SU2C Grant Funds Promising USC Cancer Research
A grant awarded three years ago by Stand Up To Cancer,a program of the Entertainment Industry Foundation,is having a positive effect on research at the USC Norris Comprehensive Cancer Center and USC Norris Cancer Hospital,Los Angeles.Five Dream Teams of researchers received the initial funding from S^2C.
We've made great progress.We could be looking at some major breakthroughs,said Peter Jones,PhD,DSc,Director of USC Norris Comprehensive Cancer Center and a Distinguished Professor at the Keck School of Medicine.
The researchers have been studying epigenetic therapy and cancer management in cancers of the lung,breast,colon and blood.Epigenetic research examines the way genes are switched on and off,and how this results in cancer.
The S^2C grant is being shared with the Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center,Baltimore.It has brought together clinicians and basic scientists for the first time at USC,providing a framework for thinking collaboratively about how to bring lab discoveries to the clinical setting.
The USC research has yielded promising new approaches in clinical trials that combine epigenetic therapy with immunotherapy and/or chemotherapy for a better patient response to treatment.
Founded in 2008,Stand Up To Cancer has awarded 109 million dollars for 33 grants,funding 350 scientists.It aims to accelerate innovative cancer research that will get new therapies to patients quickly and save lives now.
We've made great progress.We could be looking at some major breakthroughs,said Peter Jones,PhD,DSc,Director of USC Norris Comprehensive Cancer Center and a Distinguished Professor at the Keck School of Medicine.
The researchers have been studying epigenetic therapy and cancer management in cancers of the lung,breast,colon and blood.Epigenetic research examines the way genes are switched on and off,and how this results in cancer.
The S^2C grant is being shared with the Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center,Baltimore.It has brought together clinicians and basic scientists for the first time at USC,providing a framework for thinking collaboratively about how to bring lab discoveries to the clinical setting.
The USC research has yielded promising new approaches in clinical trials that combine epigenetic therapy with immunotherapy and/or chemotherapy for a better patient response to treatment.
Founded in 2008,Stand Up To Cancer has awarded 109 million dollars for 33 grants,funding 350 scientists.It aims to accelerate innovative cancer research that will get new therapies to patients quickly and save lives now.
Tuesday, October 2, 2012
Who Sings on the Internet Explorer 9 Commercial
The song is called "Too Close."It is performed by the British singer songwriter Alex Clare,27.Clare,a London native and resident,says he is a big Stevie Wonder fan.He had dated the late Amy Winehouse for a year.
Clare's most successful track to date,"Too Close" is from his debut album "The Lateness of the Hour,"which was released in July 2011.Thanks to its use in the IE9 commercial,the song reached #8 on the US Billboard Hot 100,and #4 on the UK Singles Chart.It is available on YouTube.
Described as being visually stunning,IE9 was released by Microsoft on March 14,2011.The web browser is characterised by hardware accelerated graphics and video,as well as high fidelity printing and enhanced security.It is not compatible with Windows XP.
PC World magazine ranked IE9 #19 on its Best Products of 2011 list.
Future versions of IE will only be supported on Windows 7 and later,and not on Windows Vista.
The slogan for IE9 is "Fast is now beautiful."
Microsoft(MSFT)
Clare's most successful track to date,"Too Close" is from his debut album "The Lateness of the Hour,"which was released in July 2011.Thanks to its use in the IE9 commercial,the song reached #8 on the US Billboard Hot 100,and #4 on the UK Singles Chart.It is available on YouTube.
Described as being visually stunning,IE9 was released by Microsoft on March 14,2011.The web browser is characterised by hardware accelerated graphics and video,as well as high fidelity printing and enhanced security.It is not compatible with Windows XP.
PC World magazine ranked IE9 #19 on its Best Products of 2011 list.
Future versions of IE will only be supported on Windows 7 and later,and not on Windows Vista.
The slogan for IE9 is "Fast is now beautiful."
Microsoft(MSFT)
Monday, October 1, 2012
Asia This Day:Manufacturing Declines Across Region
Manufacturing is in decline across the Asia-Pacific region,according to the latest data.In Japan,the Tankan index of large manufacturer sentiment fell to -3 from -1,the Bank of Japan reported,and there was a second straight decline of industrial production in August.
HSBC's purchasing mangers' index showed 11 straight months of manufacturing decline in China,while the official Chinese PMI charted the second straight monthly drop on diminished internal and external demand.In South Korea,exports fell 1.8% in September.
Australia is also slowing down,with its manufacturing index slipping 1.2 to 44.1,meaning contraction,in a seventh straight month of decline.China's economic growth is at a 22-year low.The European debt crisis and fears about the US economy are crimping Asian business activity.
The MSCI Asia-Pacific index fell 0.28% in early Monday trading.Markets in Hong Kong,Shanghai and Seoul were closed for holidays.
The Chinese Communist Party will hold its 18th Party Congress on November 8.At that time,new leaders Xi Jingping and Li Keqiang will take office as President and Premier,respectively.
HSBC's purchasing mangers' index showed 11 straight months of manufacturing decline in China,while the official Chinese PMI charted the second straight monthly drop on diminished internal and external demand.In South Korea,exports fell 1.8% in September.
Australia is also slowing down,with its manufacturing index slipping 1.2 to 44.1,meaning contraction,in a seventh straight month of decline.China's economic growth is at a 22-year low.The European debt crisis and fears about the US economy are crimping Asian business activity.
The MSCI Asia-Pacific index fell 0.28% in early Monday trading.Markets in Hong Kong,Shanghai and Seoul were closed for holidays.
The Chinese Communist Party will hold its 18th Party Congress on November 8.At that time,new leaders Xi Jingping and Li Keqiang will take office as President and Premier,respectively.
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